C9ORF72 anticorps (C-Term)

N° du produit ABIN6992180

Détail du produit anti-C9ORF72 anticorps

Antigène: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Épitope: AA 400-450, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C9ORF72 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificité: ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.

Purification: ALSFTD Antibody is affinity chromatography purified via peptide column.

Immunogène: ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD. The immunogen is located within amino acids 400 - 450 of ALSFTD.

Isotype: IgG

Information d'application

Indications d'application: ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ALSFTD Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ALSFTD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur C9ORF72

Antigène: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Autre désignation: ALSFTD (C9ORF72 Produits)

Synonymes: anticorps CZH9orf72, anticorps ALSFTD, anticorps FTDALS, anticorps AI840585, anticorps c9orf72, anticorps chromosome Z C9orf72 homolog, anticorps chromosome 9 open reading frame 72, anticorps RIKEN cDNA 3110043O21 gene, anticorps similar to RIKEN cDNA 3110043O21, anticorps chromosome 9 open reading frame 72 L homeolog, anticorps CZH9orf72, anticorps C9orf72, anticorps 3110043O21Rik, anticorps RGD1359108, anticorps c9orf72.L

Sujet: ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).

Poids moléculaire: Predicted: 53 kDa

Observed: 52 kDa

ID gène: 203228

NCBI Accession: NP_060795

UniProt: Q96LT7