SUSD3 anticorps (AA 120-170)

N° du produit ABIN6992182

Cet anticorps Lapin Polyclonal détecte spécifiquement SUSD3 dans ELISA, WB et ICC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour SUSD3 anticorps (AA 120-170) (ABIN6992182)

Antigène: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUSD3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Détail du produit anti-SUSD3 anticorps

Épitope: AA 120-170

Specificité: SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.

Purification: SUSD3 Antibody is affinity chromatography purified via peptide column.

Immunogène: SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3. The immunogen is located within amino acids 120 - 170 of SUSD3.

Isotype: IgG

Information d'application

Indications d'application: SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SUSD3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SUSD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SUSD3

Antigène: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Autre désignation: SUSD3

Sujet: Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).

Poids moléculaire: Predicted: 16, 22, 23, 28 kDa

Observed: 23 kDa

ID gène: 203328

NCBI Accession: NP_659443

UniProt: Q96L08