PDCD1LG2 anticorps (Extracellular Domain)

N° du produit ABIN6992226

Cet anticorps anti-PDCD1LG2 est un anticorps Souris Monoclonal détectant PDCD1LG2 dans WB, FACS, ELISA, ICC, IF et IHC (p). Adapté pour Humain.

Aperçu rapide pour PDCD1LG2 anticorps (Extracellular Domain) (ABIN6992226)

Antigène: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDCD1LG2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4E10

Détail du produit anti-PDCD1LG2 anticorps

Épitope: Extracellular Domain

Purification: PD-L2 Antibody is supplied as protein A purified IgG1.

Immunogène: PD-L2 antibody was raised against the extracellular domain of human PD-L2.

Isotype: IgG1

Information d'application

Indications d'application: PD-L2 antibody can be used for detection of PD-L2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples, Immunofluorescence in human samples and Flow Cytometry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PD-L2 Antibody is supplied in PBS containing 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PD-L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PDCD1LG2

Antigène: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Autre désignation: PDL2

Sujet: PD-L2 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through and alternative receptor from PD-1.

Poids moléculaire: Predicted: 30 kDa

Observed: 38 kDa

ID gène: 80380

NCBI Accession: NP_079515

UniProt: P9BQ51