Chromogranin A anticorps
Aperçu rapide pour Chromogranin A anticorps (ABIN7234264)
Antigène
Voir toutes Chromogranin A (CHGA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Antigen Affinity Purification
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Immunogène
- Recombinant Mouse Chromogranin-A protein
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:1000 IHC 1:100-1:300
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Chromogranin A (CHGA)
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Autre désignation
- Chromogranin A
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Sujet
- Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin,pancreastatin,catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) ,and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.
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Poids moléculaire
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Observed_MW: 51 kDa
Calculated_MW: 51 kDa
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UniProt
- P26339
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Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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