Annexin VII anticorps

N° du produit ABIN7234624

Détail du produit anti-Annexin VII anticorps

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin VII est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human ANXA7

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Annexin VII

Antigène: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Autre désignation: ANXA7 (ANXA7 Produits)

Synonymes: anticorps ANX7, anticorps SNX, anticorps SYNEXIN, anticorps AI265384, anticorps AI316497, anticorps Anx7, anticorps synexin, anticorps anxa7, anticorps MGC76267, anticorps MGC82023, anticorps ANXA7, anticorps MGC83033, anticorps annexin A7, anticorps annexin VII, anticorps annexin A7 S homeolog, anticorps ANXA7, anticorps Anxa7, anticorps anxa7, anticorps anxa7.S, anticorps PTRG_02166, anticorps BRAFLDRAFT_231082, anticorps PAAG_00136, anticorps MCYG_04180, anticorps VDBG_06328, anticorps MGYG_02426

Sujet: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.

UniProt: P20073