ALKBH1 anticorps

N° du produit ABIN7235714

L’anticorps anti-ALKBH1 Polyclonal Lapin est utilisé pour la détection de ALKBH1 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour ALKBH1 anticorps (ABIN7235714)

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ALKBH1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human ALKBH1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALKBH1

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Autre désignation: ALKBH1

Sujet: This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.

Poids moléculaire: 44 kDa

UniProt: Q13686

Pathways: Réparation de l'ADN