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USP2 anticorps

Cet anticorps anti-USP2 est un anticorps Lapin Polyclonal détectant USP2 dans ELISA et IHC. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7236025

Aperçu rapide pour USP2 anticorps (ABIN7236025)

Antigène

Voir toutes USP2 Anticorps
USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Reactivité

  • 60
  • 8
  • 7
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 58
  • 4
Lapin

Clonalité

  • 60
  • 2
Polyclonal

Conjugué

  • 34
  • 6
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp USP2 est non-conjugé

Application

  • 45
  • 31
  • 26
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogène

    Recombinant protein of human USP2

    Isotype

    IgG
  • Indications d'application

    IHC 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.3 mg/mL

    Buffer

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    USP2 (Ubiquitin Specific Peptidase 2 (USP2))

    Autre désignation

    USP2

    Sujet

    This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

    UniProt

    O75604
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