SMG8 anticorps

N° du produit ABIN7238174

Cet anticorps anti-SMG8 est un anticorps Lapin Polyclonal détectant SMG8 dans IHC et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour SMG8 anticorps (ABIN7238174)

Antigène: SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMG8 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-SMG8 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human SMG8

Isotype: IgG

Information d'application

Indications d'application: IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SMG8

Antigène: SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))

Autre désignation: SMG8

Sujet: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.

NCBI Accession: NP_060619

UniProt: Q8ND04