Pleiotrophin anticorps

N° du produit ABIN7238324

Détail du produit anti-Pleiotrophin anticorps

Antigène: Pleiotrophin (PTN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Pleiotrophin est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human PTN

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Pleiotrophin

Antigène: Pleiotrophin (PTN)

Autre désignation: PTN (PTN Produits)

Synonymes: anticorps zHBNF, anticorps zgc:111787, anticorps harp, anticorps hbnf, anticorps X-PTF, anticorps hbgf8, anticorps negf1, anticorps ptn, anticorps PTN, anticorps HARP, anticorps HBGF8, anticorps HBNF, anticorps NEGF1, anticorps PTN-A, anticorps HB-GAM, anticorps HBBM, anticorps HBGF-8, anticorps OSF-1, anticorps HBBN, anticorps OSF, anticorps Osf-1, anticorps Osf1, anticorps Hbnf, anticorps pleiotrophin, anticorps pleiotrophin L homeolog, anticorps ptn, anticorps PTN, anticorps ptn.L, anticorps Ptn

Sujet: Pleiotrophin(PTN) also known asheparin-binding brain mitogen(HBBM) orheparin-binding growth factor 8(HBGF-8) orneurite growth-promoting factor 1(NEGF1) orheparin affinity regulatory peptide(HARP) orheparin binding growth associated molecule(HB-GAM) is aproteinthat in humans is encoded by thePTNgene.Pleiotrophin is an 18- kDagrowth factorthat has a high affinity forheparin. It is structurally related tomidkineandretinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Poids moléculaire: 19 kDa

NCBI Accession: NP_002816

UniProt: P21246

Pathways: Signalisation RTK