SLC27A1 anticorps

N° du produit ABIN7238366

Détail du produit anti-SLC27A1 anticorps

Antigène: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC27A1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human SLC27A1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SLC27A1

Antigène: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Autre désignation: SLC27A1 (FATP1 Produits)

Synonymes: anticorps ACSVL5, anticorps FATP, anticorps FATP1, anticorps Fatp, anticorps FATP-1, anticorps FATP-1c, anticorps solute carrier family 27 member 1, anticorps solute carrier family 27 (fatty acid transporter), member 1, anticorps SLC27A1, anticorps Slc27a1

Sujet: The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.

NCBI Accession: NP_940982

UniProt: Q6PCB7

Pathways: Inositol Metabolic Process, Regulation of Lipid Metabolism by PPARalpha