Aconitase 1 anticorps

N° du produit ABIN7238480

Cet anticorps anti-Aconitase 1 est un anticorps Lapin Polyclonal détectant Aconitase 1 dans IHC et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Aconitase 1 anticorps (ABIN7238480)

Antigène: Aconitase 1 (ACO1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aconitase 1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-Aconitase 1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human ACO1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Aconitase 1

Antigène: Aconitase 1 (ACO1)

Autre désignation: ACO1

Sujet: Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.

NCBI Accession: NP_002188

UniProt: P21399

Pathways: Transition Metal Ion Homeostasis