L’anticorps Lapin Polyclonal anti-HTRA3 a été validé pour IHC et ELISA. Il convient pour détecter HTRA3 dans des échantillons de Humain, Rat et Souris.
HTRA3
Reactivité: Humain, Rat, Souris, Cobaye, Chien, Cheval
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC 1:50-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
HTRA3
(HtrA Serine Peptidase 3 (HTRA3))
Autre désignation
HTRA3
Sujet
HtrA3, also known as PRSP (pregnancy-related serine protease), is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.