OMG anticorps
Aperçu rapide pour OMG anticorps (ABIN7001420)
Antigène
Voir toutes OMG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Synthetic peptide of human OMG
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Isotype
- IgG
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Indications d'application
- IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- OMG (Oligodendrocyte Myelin Glycoprotein (OMG))
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Autre désignation
- OMG
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Sujet
- Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells, from dorsal root ganglion explants in which growth cone collapse was observed, from rat retinal ganglion neurons, and from NG108 and PC-12 cells.
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NCBI Accession
- NP_002535
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UniProt
- P23515
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Cell Size
Antigène
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