HIF1AN anticorps
Aperçu rapide pour HIF1AN anticorps (ABIN7239416)
Antigène
Voir toutes HIF1AN AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Synthetic peptide of human HIF1AN
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Isotype
- IgG
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anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 31-349) antibody
HIF1AN Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reactivité: Humain WB, ELISA, IF, IP Hôte: Souris Monoclonal 1D8 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 2-254) antibodyHIF1AN Reactivité: Humain WB, ELISA, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reactivité: Humain WB, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyKD Validated HIF1AN Reactivité: Humain WB, ICC, FACS Hôte: Lapin Monoclonal 23GB6385 unconjugated Recombinant Antibody
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (N-Term) antibodyHIF1AN Reactivité: Humain, Lapin, Cheval WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reactivité: Humain WB, IF Hôte: Souris Monoclonal 931CT3-1-1 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (C-Term) antibodyHIF1AN Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyKO Validated HIF1AN Reactivité: Humain WB Hôte: Lapin Monoclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 286-316), (C-Term) antibodyHIF1AN Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB10747 unconjugated
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:300
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.6 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
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Autre désignation
- HIF1AN
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Sujet
- Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
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Poids moléculaire
- 40 kDa
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NCBI Accession
- NP_060372
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UniProt
- Q9NWT6
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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