DUSP12 anticorps

N° du produit ABIN7239899

L’anticorps Lapin Polyclonal anti-DUSP12 a été validé pour ELISA et IHC. Il convient pour détecter DUSP12 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DUSP12 anticorps (ABIN7239899)

Antigène: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP12 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DUSP12 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human DUSP12

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUSP12

Antigène: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Autre désignation: DUSP12

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

UniProt: Q9UNI6

Pathways: Regulation of Carbohydrate Metabolic Process