L’anticorps Lapin Polyclonal anti-FGFR1OP a été validé pour WB, IHC et ELISA. Il convient pour détecter FGFR1OP dans des échantillons de Humain et Souris.
FGFR1OP
Reactivité: Humain, Souris, Rat, Singe
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB 1:500-1:2000, IHC 1:50-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
0.7 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
FGFR1OP
(FGFR1 Oncogene Partner (FGFR1OP))
Autre désignation
FGFR1OP
Sujet
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.