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TAB1 anticorps

TAB1 Reactivité: Humain, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7241657
  • Antigène Voir toutes TAB1 Anticorps
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    Reactivité
    • 92
    • 40
    • 28
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 96
    • 9
    • 2
    Lapin
    Clonalité
    • 100
    • 7
    Polyclonal
    Conjugué
    • 40
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TAB1 est non-conjugé
    Application
    • 69
    • 47
    • 26
    • 26
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human TAB1
    Isotype
    IgG
    Top Product
    Discover our top product TAB1 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    Autre désignation
    TAB1 (TAB1 Produits)
    Synonymes
    anticorps 3'-Tab1, anticorps MAP3K7IP1, anticorps 2310012M03Rik, anticorps Map3k7ip1, anticorps b2b449Clo, anticorps TGF-beta activated kinase 1 (MAP3K7) binding protein 1, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 1, anticorps TAB1, anticorps Tab1
    Sujet
    The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1.
    UniProt
    Q15750
    Pathways
    Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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