TAB1 anticorps
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- Antigène Voir toutes TAB1 Anticorps
- TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TAB1 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human TAB1
- Isotype
- IgG
- Top Product
- Discover our top product TAB1 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
- Autre désignation
- TAB1 (TAB1 Produits)
- Synonymes
- anticorps 3'-Tab1, anticorps MAP3K7IP1, anticorps 2310012M03Rik, anticorps Map3k7ip1, anticorps b2b449Clo, anticorps TGF-beta activated kinase 1 (MAP3K7) binding protein 1, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 1, anticorps TAB1, anticorps Tab1
- Sujet
- The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1.
- UniProt
- Q15750
- Pathways
- Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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