MCTS1 anticorps

N° du produit ABIN7241675

Cet anticorps Lapin Polyclonal détecte spécifiquement MCTS1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour MCTS1 anticorps (ABIN7241675)

Antigène: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCTS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MCTS1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human MCTS1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:1000, IHC 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCTS1

Antigène: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Autre désignation: MCTS1

Sujet: MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.

Poids moléculaire: 21 kDa

UniProt: Q9ULC4