Necdin-Like 2 anticorps

N° du produit ABIN7242953

Cet anticorps anti-Necdin-Like 2 est un anticorps Lapin Polyclonal détectant Necdin-Like 2 dans WB, ELISA et IHC. Adapté pour Humain et Souris.

Aperçu rapide pour Necdin-Like 2 anticorps (ABIN7242953)

Antigène: Necdin-Like 2 (NDNL2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Necdin-Like 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Necdin-Like 2 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human NDNL2

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:5000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Necdin-Like 2

Antigène: Necdin-Like 2 (NDNL2)

Autre désignation: NSMCE3

Sujet: The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).

Poids moléculaire: 34 kDa

NCBI Accession: NP_619649

UniProt: Q96MG7