L’anticorps Lapin Polyclonal anti-HMGCS2 a été validé pour WB, ELISA et IHC. Il convient pour détecter HMGCS2 dans des échantillons de Humain et Souris.
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.