ARIH1 anticorps

N° du produit ABIN7003436

Détail du produit anti-ARIH1 anticorps

Antigène: ARIH1 (Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARIH1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human ARIH1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARIH1

Antigène: ARIH1 (Ariadne Homolog, Ubiquitin-Conjugating Enzyme E2 Binding Protein, 1 (ARIH1))

Autre désignation: ARIH1 (ARIH1 Produits)

Synonymes: anticorps ARIH1, anticorps ARI-1, anticorps ari, anticorps ariadne, anticorps hari, anticorps hhari, anticorps ubch7bp, anticorps ARI, anticorps HARI, anticorps HHARI, anticorps UBCH7BP, anticorps AU021774, anticorps Ari, anticorps Ari1, anticorps Hari, anticorps Hhari, anticorps Ubch7bp, anticorps Uip77, anticorps wu:fa18d01, anticorps zgc:66364, anticorps ariadne RBR E3 ubiquitin protein ligase 1, anticorps ariadne RBR E3 ubiquitin protein ligase 1 L homeolog, anticorps ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila), anticorps Arih1, anticorps ARIH1, anticorps arih1, anticorps arih1.L

Sujet: ARIH1 (ariadne homolog), also known as ubiquitin conjugating enzyme E2 binding protein 1, ARI, HARI, HHARI (human homolog of Drosophila ariadne), MOP-6 (monocyte protein 6) or UBCH7BP (UBCH7 binding protein), is a 557 amino acid cytoplasmic protein. Expressed in a wide variety of tissues, ARIH1 contains two RING-type zinc fingers and one IBR (in-between RING fingers)-type domain. ARIH1 is believed to be involved in protein degradation and protein translation. ARIH1 interacts with UBCH7 and is thought to function as an E3 ubiquitin-protein ligase (or as a component of an E3 complex) that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme (UBCH7) and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, ARIH1 interacts with and polyubiquitylates eIF4E2, thereby targeting it for proteasomal degradation.

UniProt: Q9Y4X5