APC anticorps

N° du produit ABIN7244711

Cet anticorps Lapin Polyclonal détecte spécifiquement APC dans IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour APC anticorps (ABIN7244711)

Antigène: APC (Adenomatous Polyposis Coli (APC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-APC anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human APC

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur APC

Antigène: APC (Adenomatous Polyposis Coli (APC))

Autre désignation: APC

Sujet: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

UniProt: P25054

Pathways: Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization