KDM2A anticorps

N° du produit ABIN7244933

Cet anticorps Lapin Polyclonal détecte spécifiquement KDM2A dans ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour KDM2A anticorps (ABIN7244933)

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM2A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-KDM2A anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human KDM2A

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.62 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KDM2A

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Autre désignation: KDM2A

Sujet: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.

UniProt: Q9Y2K7

Pathways: L'effet Warburg