Lactate Dehydrogenase A anticorps

N° du produit ABIN7245125

Cet anticorps Lapin Polyclonal détecte spécifiquement Lactate Dehydrogenase A dans WB, IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Lactate Dehydrogenase A anticorps (ABIN7245125)

Antigène: Lactate Dehydrogenase A (LDHA)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lactate Dehydrogenase A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Lactate Dehydrogenase A anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human LDHA

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Lactate Dehydrogenase A

Antigène: Lactate Dehydrogenase A (LDHA)

Autre désignation: LDHA

Sujet: LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 37 kDa

UniProt: P00338

Pathways: L'effet Warburg