Lactate Dehydrogenase A anticorps

N° du produit ABIN7245125

Détail du produit anti-Lactate Dehydrogenase A anticorps

Antigène: Lactate Dehydrogenase A (LDHA)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lactate Dehydrogenase A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human LDHA

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Lactate Dehydrogenase A

Antigène: Lactate Dehydrogenase A (LDHA)

Autre désignation: LDHA (LDHA Produits)

Synonymes: anticorps GSD11, anticorps LDH1, anticorps LDHM, anticorps LDH-M, anticorps ldh-h, anticorps ldha, anticorps ldha-B, anticorps ldhbb, anticorps trg-5, anticorps Ldh1, anticorps Ldhm, anticorps l7R2, anticorps gsd11, anticorps ldh-m, anticorps ldh1, anticorps ldhm, anticorps pig19, anticorps ldha1, anticorps ldhab, anticorps LDH-A, anticorps LDHC, anticorps lactate dehydrogenase A, anticorps lactate dehydrogenase B L homeolog, anticorps lactate dehydrogenase A4, anticorps lactate dehydrogenase A L homeolog, anticorps L-lactate dehydrogenase A chain, anticorps LDHA, anticorps ldhb.L, anticorps Ldha, anticorps ldha, anticorps ldha.L, anticorps LOC100713875

Sujet: LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 37 kDa

UniProt: P00338

Pathways: L'effet Warburg