CBP anticorps

N° du produit ABIN7245413

Cet anticorps anti-CBP est un anticorps Lapin Polyclonal détectant CBP dans IHC et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CBP anticorps (ABIN7245413)

Antigène: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-CBP anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human CREBBP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CBP

Antigène: CBP (CREBBP) (CREB Binding Protein (CREBBP))

Autre désignation: CREBBP

Sujet: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q92793

Pathways: TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha