BAIAP2L1 anticorps

N° du produit ABIN7246010

Cet anticorps anti-BAIAP2L1 est un anticorps Lapin Polyclonal détectant BAIAP2L1 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour BAIAP2L1 anticorps (ABIN7246010)

Antigène: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAIAP2L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-BAIAP2L1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human BAIAP2L1

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:5000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BAIAP2L1

Antigène: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Autre désignation: BAIAP2L1

Sujet: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 57 kDa

UniProt: Q9UHR4

Pathways: Regulation of Actin Filament Polymerization