SETMAR anticorps

N° du produit ABIN7247045

Détail du produit anti-SETMAR anticorps

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETMAR est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human SETMAR

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.08 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SETMAR

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Autre désignation: SETMAR (SETMAR Produits)

Synonymes: anticorps HsMar1, anticorps METNASE, anticorps Mar1, anticorps 5830404F24Rik, anticorps Etet2, anticorps SETMAR, anticorps zgc:172212, anticorps SET domain and mariner transposase fusion gene, anticorps SET domain without mariner transposase fusion, anticorps histone-lysine N-methyltransferase SETMAR, anticorps SETMAR, anticorps Setmar, anticorps LOC470738, anticorps setmar, anticorps LOC703880, anticorps LOC100447656, anticorps LOC100586616

Sujet: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus