SETMAR anticorps
Aperçu rapide pour SETMAR anticorps (ABIN7262651)
Antigène
Voir toutes SETMAR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human SETMAR (NP_006506.3).
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Isotype
- IgG
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Indications d'application
- IF 1:20-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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Autre désignation
- SETMAR
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Sujet
- This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
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ID gène
- 6419
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UniProt
- Q53H47
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Antigène
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