SF3B3 anticorps

N° du produit ABIN7247129

L’anticorps Lapin Polyclonal anti-SF3B3 a été validé pour ELISA et IHC. Il convient pour détecter SF3B3 dans des échantillons de Humain et Souris.

Aperçu rapide pour SF3B3 anticorps (ABIN7247129)

Antigène: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SF3B3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SF3B3 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human SF3B3

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SF3B3

Antigène: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Autre désignation: SF3B3

Sujet: This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

UniProt: Q15393