IGLL1 anticorps

N° du produit ABIN7247582

Détail du produit anti-IGLL1 anticorps

Antigène: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGLL1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human IGLL1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IGLL1

Antigène: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Autre désignation: IGLL1 (IGLL1 Produits)

Synonymes: anticorps 14.1, anticorps AGM2, anticorps CD179b, anticorps IGL1, anticorps IGL5, anticorps IGLJ14.1, anticorps IGLL, anticorps IGO, anticorps IGVPB, anticorps VPREB2, anticorps IGLV, anticorps IGLL1, anticorps MGC151892, anticorps Igll1, anticorps BB139905, anticorps Igl-5, anticorps Igll, anticorps Lambda5, anticorps immunoglobulin lambda like polypeptide 1, anticorps immunoglobulin lambda-like polypeptide 1, anticorps IGLL1, anticorps Igll1

Sujet: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.IGLL1 (Immunoglobulin Lambda Like Polypeptide 1) is a Protein Coding gene. Diseases associated with IGLL1 include Agammaglobulinemia 2 and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Cell surface interactions at the vascular wall and Primary immunodeficiency. An important paralog of this gene is IGLL5.

UniProt: P15814

Pathways: Regulation of Cell Size