GLI1 anticorps
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- Antigène Voir toutes GLI1 Anticorps
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GLI1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogène
- Synthetic peptide of human GLI1
- Isotype
- IgG
- Top Product
- Discover our top product GLI1 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.08 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- Autre désignation
- GLI1 (GLI1 Produits)
- Synonymes
- anticorps GLI, anticorps Gli, anticorps Gli-1, anticorps gli1.1, anticorps AV235269, anticorps Zfp-5, anticorps Zfp5, anticorps GLI family zinc finger 1, anticorps GLI family zinc finger 1 S homeolog, anticorps GLI-Kruppel family member GLI1, anticorps GLI1, anticorps Gli1, anticorps gli1.S, anticorps gli1
- Sujet
- GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
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Observed_MW: Refer to figures
Calculated_MW: 118 kDa
- UniProt
- P08151
- Pathways
- Signalisation Hedgehog, Dopaminergic Neurogenesis
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