ORAI1 anticorps
Aperçu rapide pour ORAI1 anticorps (ABIN7005056)
Antigène
Voir toutes ORAI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Synthetic peptide of human ORAI1(L1)
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Isotype
- IgG
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Indications d'application
- WB 1:200-1000, ELISA 1:1000-2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.3 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
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Autre désignation
- ORAI1
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Sujet
- The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
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Poids moléculaire
- 33 kDa
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NCBI Accession
- NP_116179
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UniProt
- Q96D31
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Pathways
- TCR Signaling, BCR Signaling
Antigène
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