CREBZF anticorps
Aperçu rapide pour CREBZF anticorps (ABIN7249328)
Antigène
Voir toutes CREBZF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Attributs du produit
- Polyclonal Antibody
-
Purification
- Antigen affinity purification
-
Immunogène
- Synthetic peptide of human CREBZF
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.4 mg/mL
-
Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))
-
Autre désignation
- CREBZF
-
Sujet
- Host cell factor (HCF) is a cellular cofactor required for the activation of VP16 which expresses the herpes simplex virus immediate early gene. V16 binds to HCF through a 4-amino acid motif similar to the HCF binding domain of the basic leucine-zipper proteins Luman and Zhangfei (ZF). Luman activates promoters containing cAMP or unfolded protein response elements (UPRE). Zhangfei suppresses the transcriptional activity of Luman, but requires HCF binding which may target Luman and Zhangfei to a common location. Sequence analysis predicts that the deduced 272-amino acid Zhangfei protein has a negatively charged N terminus, a leucine zipper of 6 heptad leucine repeats separated by a conserved 6-amino acid spacer, a basic domain, and a bZIP region. It is also presumed that the N-terminal acidic region of Zhangfei is an activation domain.
-
Poids moléculaire
-
Observed_MW: Refer to figures
Calculated_MW: 37 kDa
-
UniProt
- Q9NS37
Antigène
-