NOS1 anticorps
Aperçu rapide pour NOS1 anticorps (ABIN7249462)
Antigène
Voir toutes NOS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse nNOS
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:300-1:800
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 350 μg/mL
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Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
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Autre désignation
- NOS1
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Sujet
- The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
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Poids moléculaire
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Observed_MW: 161 kDa
Calculated_MW: 161 kDa
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UniProt
- P29475, P29476, Q9Z0J4
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Pathways
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
Antigène
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