AFT1 anticorps
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- Antigène Voir toutes AFT1 Anticorps
- AFT1 (Activating Transcription Factor 1 (AFT1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AFT1 est non-conjugé
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Application
- Western Blotting (WB)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse ATF1
- Isotype
- IgG
- Top Product
- Discover our top product AFT1 Anticorps primaire
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- Indications d'application
- WB 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.59 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- AFT1 (Activating Transcription Factor 1 (AFT1))
- Autre désignation
- ATF1 (AFT1 Produits)
- Synonymes
- anticorps ews-atf1, anticorps fus/atf-1, anticorps treb36, anticorps ATF1, anticorps EWS-ATF1, anticorps FUS/ATF-1, anticorps TREB36, anticorps Atf-1, anticorps wu:fc92c07, anticorps zgc:64099, anticorps activating transcription factor 1, anticorps activating transcription factor 1 L homeolog, anticorps atf1, anticorps ATF1, anticorps MGC85066, anticorps atf1.L, anticorps Atf1
- Sujet
- This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
- Poids moléculaire
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Observed_MW: 29 kDa
Calculated_MW: 29 kDa
- UniProt
- P18846, P81269
- Pathways
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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