NFKBIB anticorps

N° du produit ABIN7249640

Détail du produit anti-NFKBIB anticorps

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFKBIB est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse IKBbeta

Isotype: IgG

Information d'application

Indications d'application: IHC 1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NFKBIB

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Autre désignation: NFKBIB (NFKBIB Produits)

Synonymes: anticorps NFKBIB, anticorps IKB-beta, anticorps IKappaBbeta, anticorps IkB, anticorps IkBb, anticorps IKBB, anticorps TRIP9, anticorps NFKB inhibitor beta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta, anticorps NFKBIB, anticorps Nfkbib

Sujet: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.

UniProt: Q15653, Q60778, Q9JIA3

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades