beta Catenin anticorps
Aperçu rapide pour beta Catenin anticorps (ABIN7249752)
Antigène
Voir toutes beta Catenin (CATNB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Monoclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse beta-catenin
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:1000, IHC 1:100-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 420 μg/mL
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Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Autre désignation
- Catenin beta
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Sujet
- CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
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Poids moléculaire
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Observed_MW: 92 kDa
Calculated_MW: 92 kDa
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UniProt
- P35222, Q02248, Q9WU82
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Pathways
- Peptide Hormone Metabolism
Antigène
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