PNKP anticorps (AA 51-160) (HRP)

N° du produit ABIN700549

Cet anticorps Lapin Polyclonal détecte spécifiquement PNKP dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour PNKP anticorps (AA 51-160) (HRP) (ABIN700549)

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNKP est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PNKP anticorps (HRP)

Épitope: AA 51-160

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PNK1/PNKP

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PNKP

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Autre désignation: PNK1/PNKP

Sujet:

Synonyms: Bunctional polynucleotide phosphatase/kinase, DEM 1, DEM1, DNA 5' kinase/3' phosphatase, PNK 1, PNK, PNK1, PNKP, Polynucleotide 5' hydroxyl kinase, Polynucleotide kinase 3 prime phosphatase, Polynucleotide kinase 3' phosphatase, Polynucleotide Kinase, PNKP_HUMAN.

Background: Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage.PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.

ID gène: 11284

Pathways: Réparation de l'ADN, Nucleotide Phosphorylation