AMACR anticorps
Aperçu rapide pour AMACR anticorps (ABIN7250047)
Antigène
Voir toutes AMACR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Monoclonal Antibody
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Purification
- Protein A purification
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Immunogène
- Synthetic Peptide
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Autre désignation
- AMACR
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Sujet
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
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Poids moléculaire
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Observed_MW: 42 kDa
Calculated_MW: 42 kDa
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UniProt
- Q9UHK6
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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