ACTN1 anticorps

N° du produit ABIN7250311

Cet anticorps Souris Monoclonal détecte spécifiquement ACTN1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ACTN1 anticorps (ABIN7250311)

Antigène: ACTN1 (Actinin, alpha 1 (ACTN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACTN1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1D4

Détail du produit anti-ACTN1 anticorps

Attributs du produit: Monoclonal Antibody

Purification: Protein A purification

Immunogène: Recombinant Protein of a-actinin of ACTN1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ACTN1

Antigène: ACTN1 (Actinin, alpha 1 (ACTN1))

Autre désignation: ACTN1

Sujet: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

UniProt: P12814

Pathways: Cell-Cell Junction Organization