beta Catenin anticorps (pTyr654)
Aperçu rapide pour beta Catenin anticorps (pTyr654) (ABIN7250716)
Antigène
Voir toutes beta Catenin (CATNB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr654
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Attributs du produit
- Phosphorylated antibody
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Purification
- Affinity purification
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Immunogène
- Synthesized peptide derived from human Catenin-beta around the phosphorylation site of Tyr654
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Isotype
- IgG
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anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB Reactivité: Humain, Souris, Rat WB, FACS, IF (cc), ELISA, IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 661-781) antibodyCATNB Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Porc WB, FACS, IF (cc), ELISA, IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reactivité: Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Porc, Lapin, Mouton, Singe, Hamster, Avian, Cat, Âne, Chévre, Cobaye, Cheval WB, IF Hôte: Chèvre Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reactivité: Humain, Poisson zèbre (Danio rerio) WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibodyCATNB Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reactivité: Humain WB, IHC, IP, ICC Hôte: Souris Monoclonal C11 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reactivité: Humain, Souris, Hamster WB, IP, ICC, ICFC Hôte: Souris Monoclonal EM-22 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reactivité: Humain, Souris, Rat WB, IHC Hôte: Souris Monoclonal 4A3H3 unconjugated
anti-Catenin, beta (CATNB) (AA 764-781) antibodyCATNB Reactivité: Humain, Souris, Rat WB, IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Autre désignation
- Catenin beta
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Sujet
- Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
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Poids moléculaire
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Observed_MW: 75 kDa
Calculated_MW: 85 kDa
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Antigène
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