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RCC1 anticorps (AA 11-120)

RCC1 Reactivité: Humain ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN700585
  • Antigène Voir toutes RCC1 Anticorps
    RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
    Épitope
    • 22
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-120
    Reactivité
    • 67
    • 22
    • 21
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 57
    • 8
    • 2
    Lapin
    Clonalité
    • 60
    • 7
    Polyclonal
    Conjugué
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp RCC1 est non-conjugé
    Application
    • 43
    • 25
    • 25
    • 14
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RCC1
    Isotype
    IgG
    Top Product
    Discover our top product RCC1 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
    Autre désignation
    RCC1 (RCC1 Produits)
    Synonymes
    anticorps Chc1, anticorps zgc:65796, anticorps zgc:77114, anticorps wu:fj77f08, anticorps rcc1, anticorps chc1-a, anticorps BJ1, anticorps CG10480, anticorps CG18640 (Bj1), anticorps Dmel\\CG10480, anticorps RCC1, anticorps RanGEF, anticorps Rcc1, anticorps dRCC1, anticorps inxs, anticorps sdt, anticorps xrcc1, anticorps chc1-b, anticorps MGC115703, anticorps MGC132085, anticorps CHC1, anticorps RCC1-I, anticorps SNHG3-RCC1, anticorps 4931417M11Rik, anticorps AI326872, anticorps regulator of chromosome condensation 1, anticorps regulator of chromosome condensation 1 L homeolog, anticorps Regulator of chromosome condensation 1, anticorps N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted, anticorps regulator of chromosome condensation 1 S homeolog, anticorps rcc1, anticorps RCC1, anticorps rcc1.L, anticorps Rcc1, anticorps rcc1.S
    Sujet

    Synonyms: Cell cycle regulatory protein, CHC 1, CHC1, Chromosome condensation 1, Chromosome condensation protein 1, Guanine nucleotide releasing protein, Ran GEF, RanGEF, RCC 1, RCC1 I, Regulator of chromosome condensation 1, Regulator of chromosome condensation, SHEP1.

    Background: Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis. The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin. RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1, with chromatin , but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, and, where bound, to increase the affinity of chromatin for NE membranes.

    ID gène
    1104
    UniProt
    P18754
    Pathways
    Chromatin Binding, Protein targeting to Nucleus
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