RYR2 anticorps

N° du produit ABIN7251385

Détail du produit anti-RYR2 anticorps

Antigène: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RYR2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of Ser2808.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RYR2

Antigène: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Autre désignation: RYR2 (RYR2 Produits)

Synonymes: anticorps RYR2, anticorps ARVC2, anticorps ARVD2, anticorps RYR-2, anticorps RyR, anticorps VTSIP, anticorps 9330127I20Rik, anticorps ryanodine receptor 2, anticorps ryanodine receptor 2, cardiac, anticorps RYR2, anticorps Ryr2

Sujet: This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.

Poids moléculaire:

Observed_MW: 200-300 kDa

Calculated_MW: 564 kDa

UniProt: Q92736

Pathways: Myometrial Relaxation and Contraction