EDARADD anticorps

N° du produit ABIN7252072

L’anticorps anti-EDARADD Polyclonal Lapin est utilisé pour la détection de EDARADD dans des échantillons de Humain. Il a été validé pour ELISA et IHC.

Aperçu rapide pour EDARADD anticorps (ABIN7252072)

Antigène: EDARADD (EDAR-Associated Death Domain (EDARADD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDARADD est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EDARADD anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Full length fusion protein

Isotype: IgG

Information d'application

Indications d'application: IHC 1:35-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EDARADD

Antigène: EDARADD (EDAR-Associated Death Domain (EDARADD))

Autre désignation: EDARADD

Sujet: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

UniProt: Q8WWZ3

Pathways: Ubiquitin Proteasome Pathway