TNNT1 anticorps

N° du produit ABIN7254007

Détail du produit anti-TNNT1 anticorps

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human TNNT1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:50, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TNNT1

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Autre désignation: TNNT1 (TNNT1 Produits)

Synonymes: anticorps ANM, anticorps NEM5, anticorps STNT, anticorps TNT, anticorps TNTS, anticorps TNNI1, anticorps AW146156, anticorps Tnt, anticorps sTnT, anticorps ssTnT, anticorps Fang2, anticorps tnTs, anticorps Tnnt, anticorps zgc:193831, anticorps zgc:193865, anticorps troponin T1, slow skeletal type, anticorps troponin I1, slow skeletal type, anticorps troponin T1, skeletal, slow, anticorps troponin T1, slow skeletal type S homeolog, anticorps troponin T type 1 (skeletal, slow), anticorps TNNT1, anticorps TNNI1, anticorps Tnnt1, anticorps tnnt1.S, anticorps tnnt1

Sujet: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 33 kDa

UniProt: P13805