TNNT1 anticorps

N° du produit ABIN7231858

L’anticorps anti-TNNT1 Polyclonal Lapin est utilisé pour la détection de TNNT1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour TNNT1 anticorps (ABIN7231858)

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TNNT1 anticorps

Fonction: Rabbit Anti-TNNT1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TNNT1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human TNNT1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TNNT1

Antigène: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Autre désignation: TNNT1

Sujet: Troponin T, slow skeletal muscle, TnTs, Slow skeletal muscle troponin T, sTnTTNNT1 (Troponin T1, Slow Skeletal Type) encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in TNNT1 cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for TNNT1.

Poids moléculaire: 30kD

ID gène: 7138

UniProt: P13805