Neurofibromin 1 anticorps

N° du produit ABIN7254607

L’anticorps Lapin Polyclonal anti-Neurofibromin 1 a été validé pour ELISA et IHC. Il convient pour détecter Neurofibromin 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Neurofibromin 1 anticorps (ABIN7254607)

Antigène: Neurofibromin 1 (NF1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurofibromin 1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Neurofibromin 1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human NF1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:250, ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: NF1

Sujet: This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type 1. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and RET signaling. GO annotations related to this gene include binding and phosphatidylcholine binding.

UniProt: P21359

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity