Neurofibromin 1 anticorps
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- Antigène Voir toutes Neurofibromin 1 (NF1) Anticorps
- Neurofibromin 1 (NF1)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Neurofibromin 1 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogène
- Synthetic peptide of human NF1
- Isotype
- IgG
- Top Product
- Discover our top product NF1 Anticorps primaire
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- Indications d'application
- IHC 1:40-1:250, ELISA 1:500-1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.7 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Neurofibromin 1 (NF1)
- Autre désignation
- NF1 (NF1 Produits)
- Synonymes
- anticorps NFNS, anticorps VRNF, anticorps WSS, anticorps CG8318, anticorps Dmel\\CG8318, anticorps NF-1, anticorps NF1, anticorps Nf-1, anticorps dNF1, anticorps nf1, anticorps fe06d03, anticorps hm:zehn0874, anticorps wu:fe06d03, anticorps zehn0874, anticorps AW494271, anticorps E030030H24Rik, anticorps neurofibromin 1, anticorps Neurofibromin 1, anticorps neurofibromin 1a, anticorps neurofibromin, anticorps putative neurofibromin, anticorps NF1, anticorps Nf1, anticorps nf1a, anticorps LOC593418, anticorps LOC5570549, anticorps CpipJ_CPIJ011774, anticorps Smp_148460
- Sujet
- This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type 1. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and RET signaling. GO annotations related to this gene include binding and phosphatidylcholine binding.
- UniProt
- P21359
- Pathways
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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